Monday, August 31, 2009


A biomarker can be defined as measuring tool of a biological state that is used to objectively measure a biological process or condition. This can be a classification, score or index of various types of measurements. Biomarkers are also used to predict a response to specific therapies, used to group patients as responders and non-responders. Historically biomarkers are single whole molecules, such as the prostate-specific antigen (PSA), used in prostate cancer testing.
Arrayit's microarray technology, in used since 1997, is transforming biomarker testing techniques from single analyte tests to a more reliable multi-analyte microarray based tests. Microarrays are miniturized devices sort of like computer processors, only biological.
Just like the old saying, "two heads are better than one", we use multiple biomarkers in a single test using a microarray to make more reliable "biological decisions" (see video below for more information). We make the tests miniturized to make them inexpensive and higher throughput. All different types of molecules, including RNA, miRNA, DNA, proteins, lipids and carbohydrates are being used (see Microarray assays fall into the FDA regulated catagory of In Vitro Diagnostic Multivariate Index Assays. Microarrays are a driving force behind the movement towards personalized medicine.