Friday, August 30, 2013

Peptide Microarrays

Arrayit has a proprietary set of microarray manufacturing technology, surface chemistry, buffer systems and peptide synthesis methods it applies to delivering best in class peptide microarrays to our customers. One of our key pieces of technology is our method and design patent on the microarray manufacturing device, USPTO 6,101,946. Arrayit is the sole licensee and exclusive provider of this technology to the microarray industry. Since we are the inventors of microarray manufacturing methods, we are in the best position to deploy the technology. In addition, the surface chemistry, peptide synthesis, buffer systems and ex-situ manufacturing methods are specifically engineered to work together to selectively attach the N terminus of the peptide covalently bound to the glass at the same time providing and amide C terminus to allow for easy binding of proteins in solution to the peptides on the microarray. This covalent attachment method also allows for very stringent processing of the microarrays, critical for reporting the most accurate peptide microarray data possible. Because our microarray manufacturing methods are "ex-situ" every peptide on the microarray is quality controlled by mass spectrometry to assure that each peptide is correctly made. To our knowledge Arrayit is the only manufacturer that provides this level of quality assurance and manufacturing methods, controlling the spotting device, surface chemistry, buffer system and peptide synthesis all designed specifically for this application..all under our manufacturing control.

So if there is a problem, we do not have to look to outside supply sources. Other companies may deploy other manufacturing manufacturing methods, but not manufacture their own devices, surface chemistry buffer systems. This provides Arrayit a unique and strategic advantage in quality control. In-situ manufacturing methods are not capable of enabling this level of quality control. All microarray manufacturing is done in a class 100 clean room. Arrayit's ex-situ microarray manufacturing methods are universal enough to meet the needs of any microarray hybridization and detection platform.